By Joi B. Carter, Amrita Goyal, Lyn McDivitt Duncan
This atlas includes first-class medical and histopathologic photographs and textual content of every of the kinds of cutaneous lymphoma (around 25 entities). it's the first go-to textual content if you happen to are contemplating a analysis of cutaneous lymphoma of their differential analysis. The textual content additionally comprises diagnostic mimics of lymphoma and differential prognosis tables and algorithms. the objective viewers is basic practitioners, dermatologists, pathologists and scholars, citizens and fellows. The prognosis of lymphoma within the epidermis is confounded by means of the myriad of issues which can mimic lymphoma clinically and histopathologically and through inconsistencies within the diagnostic type that experience only in the near past been resolved. within the final decade the eu association for learn and remedy of melanoma (EORTC) Cutaneous Lymphoma team and the area well-being association (WHO) Collaborated in a sequence of workshops and consensus conferences to reach at a definitive category scheme for cutaneous lymphoma. regrettably, the e-book through the WHO that defined this schema incorporated all lymphomas and has the outside tumors scattered through the quantity. there's at present no visit textual content if you happen to are contemplating a prognosis of cutaneous lymphoma of their differential analysis. consequently there is still confusion concerning the analysis of cutaneous lymphoma, even though this type scheme used to be released in 2008.
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Additional info for Atlas of Cutaneous Lymphomas: Classification and Differential Diagnosis
Small-plaque parapsoriasis has little to no potential to evolve into MF, and it is no longer considered part of the MF spectrum by many clinicians . 5 Mycosis Fungoides 33 a b c d Fig. 1 Patch and plaque stage mycosis fungoides (MF), clinical photographs. (a) Large, pink-to-red, scaly patches and thin plaques on the flank and axilla of a 56-year-old man with patch/plaque MF. 1). (b) Numerous pink, minimally scaly macules, papules, and patches on the flank of a 57-year-old woman with patch/ plaque MF currently undergoing treatment with nitrogen mustard.
Histopathology must be combined with immunohistochemistry and clinical correlation in the diagnosis. 1 Histopathology By definition, all cutaneous lymphomas are composed of lymphocytic infiltrates involving some component of the skin. The overarching pattern of infiltration can be divided into four major categories: epidermotropic, dermal, subcutaneous, and/or angioinvasive, based on the location of the infiltrate (see Fig. 2). Some lymphomas may demonstrate one or more of these patterns, but this can serve as a reasonable diagnostic starting point.
16. Nakayama F, Nishihara S, Iwasaki H, Kudo T, Okubo R, Kaneko M, et al. CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX but in promyelocytes and monocytes by alpha 1,3-fucosyltransferase IV. J Biol Chem. 2001;276: 16100–6. 17. Benner MF, Jansen PM, Meijer CJLM, Willemze R. Diagnostic and prognostic evaluation of phenotypic markers TRAF1, MUM1, BCL2 and CD15 in cutaneous CD30-positive lymphoproliferative disorders. Br J Dermatol. 2009;161:121–7. 18. Eberle FC, Song JY, Xi L, Raffeld M, Harris NL, Wilson WH, et al.
Atlas of Cutaneous Lymphomas: Classification and Differential Diagnosis by Joi B. Carter, Amrita Goyal, Lyn McDivitt Duncan